Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function

Lipid-Coated Gold Nanoparticle as a Biosensor for Lipid-Protein Interactions

A Novel Ionizable Cationic Lipid Nanoparticle-based Delivery System for Potential RNAi Therapy in Age-related Cartilage Degradation

Heng Wu; Zhijun Yang; Doris W.T. AU; Baosheng Guo; Zihong Lin; Zhong Liu; Fangyuan Wei; Gang Li; Weimin Liao; Ling Qin; Leungkim Hung; +Lei Wei; +Ge Zhang + Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China, Department of Biology and chemistry, City University of Ho...

Alcohol Interactions with Lipid Bilayers.

We investigate the structural changes to lipid membrane that ensue from the addition of aliphatic alcohols with various alkyl tail lengths. Small angle neutron diffraction from flat lipid bilayers that are hydrated through water vapor has been employed to eliminate possible artefacts of the membrane curvature and the alcohol's membrane-water partitioning. We have observed clear changes to membr...

Lipid-protein interactions.

Intrinsic membrane proteins are solvated by a shell of lipid molecules interacting with the membrane-penetrating surface of the protein; these lipid molecules are referred to as annular lipids. Lipid molecules are also found bound between transmembrane α-helices; these are referred to as non-annular lipids. Annular lipid binding constants depend on fatty acyl chain length, but the dependence is...

Protein-Lipid Interactions - ReadingSample

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